Corticosteroids for Multiple Myeloma

Medically reviewed by: Craig Cole, MD

Last Updated: August 2026

 

Corticosteroids, often called steroids, are medicines that can help kill myeloma cells when used in larger amounts. They also help reduce side effects from chemotherapy, such as nausea and vomiting. Some steroids are also used to treat inflammation, which is swelling or irritation in the body.

There are different types of corticosteroids used for multiple myeloma. New drugs become available all the time, so this may not be a complete list.  

Please note: The side effects listed here do not represent a comprehensive list. Each drug has its own set of side effects and ways of working. It's important to discuss all potential side effects with your healthcare team. Be sure to tell them about any side effects you have.  

 

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All Available Treatments

IV (through a vein) =      Pill =

Treatment Type

Corticosteroids

Drug Names
(Dexamethasone) Decadron® (Pill)
(Prednisone) Deltasone®, Rayos®, Sterapred® (Pill)
Potential Side Effects
Blood sugar changes Blood pressure changes Infections Muscle pain Joint pain/stiffness Eye problems Ulcers/stomach problems Weight/appetite changes Swelling Agitation/anxiety/depression Sleeping problems Increased sweating
Important Things to Know
  • When corticosteroids are used for a long time, they can also suppress your immune system, which increases the risk of serious infections.  
  • Steroids can also weaken your bones.
  • Most of these side effects go away over time after the drug is stopped